Neonatal Renal Disorder

Acute renal failure (ARF) is a very common problem in the neonatal intensive care unit. The new-born kidney has a very low glomerular filtration rate (GFR) that is maintained by a delicate balance between vasoconstrictor and vasodilatory forces. Although sufficient for growth and development under normal conditions, the low GFR of the new-born kidney limits postnatal renal functional adaptation to endogenous and exogenous stresses. This limited response predisposes the new-born to the development of ARF and is even more pronounced in the low birth weight infant (ie, <2,500 g due to preterm birth or intrauterine growth restriction). Given this predisposition, early identification of ARF in the neonate is essential to preserving renal function.


  • Peritoneal dialysis
  • Renal tubular acidosis
  • Systemic Lupus Nephritis
  • Urinary tract infections
  • End stage renal failure
  • Glomerulonephritis
  • Chronic renal failure in neonates
  • Nephrotic syndrome
  • Neonetal ECG basics and common problems
  • Proteinuria


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